What organ is primarily responsible for removing waste from blood?

The kidneys are the organs primarily responsible for removing waste from the blood. Their main function is to filter the blood and eliminate waste products through urine. This process involves the removal of excess ions, toxins, and metabolic waste, such as urea, which results from protein metabolism. The kidneys also play a vital role in regulating fluid balance, electrolytes, and blood pressure, contributing to overall homeostasis in the body.

While other organs, such as the liver and lungs, help in processing or eliminating certain types of waste (like detoxifying substances or expelling carbon dioxide), the kidneys are specifically designed for the filtration of blood and excretion of urine, making them the primary organ for waste removal from the bloodstream.